Monitoring van de ketonwaarde (bij voorkeur in bloed) wordt aanbevolen. Herstart de behandeling met empagliflozine als de toestand van de patiënt stabiel is, en de ketonwaarde normaal. Er zijn meldingen van Fournier-gangreen (necrotiserende fasciitis van het perineum) bij gebruik van SGLT2-remmers.
9/17/2019 · Empagliflozin is a selective inhibitor of sodium-glucose cotransporter-2 (SGLT2) that acts by decreasing renal glucose reabsorption and increasing urinary glucose excretion.
5/9/2017 · Inspired by animal studies showing effect of a sodium-glucose cotransporter-2 (SGLT-2) inhibitor (empagliflozin) on oxidative stress and a recent trial evaluating empagliflozin that demonstrated improved cardiovascular outcomes in patients with T2D at high risk of cardiovascular events, we hypothesise that empagliflozin lowers oxidative stress.
1/12/2018 · The FPG concentration (the mean of four determinations performed on days 5, 4, 2, and 1 before the start of empagliflozin ) was 195 ± 9 mg/dL this decreased to 169 ± 11 mg/dL (difference from baseline mean, 25 ± 6 mg/dL) and to 165 ± 7 mg/dL (difference from baseline mean, 29 ± 6 mg/dL) at 24 hours and 48 hours after starting empagliflozin (both P < 0.001).Supplement to: Zinman B, Wanner C, Lachin J, et al. Empagliflozin , Cardiovascular Outcomes and Mortality in Type 2 Diabetes. N Engl J Med. Table of Contents, Empagliflozin improved cardiovascular death or heart failure hospitalization risk across the range of baseline health status. Empagliflozin improved health status across various domains, and this benefit was sustained during long-term follow-up. Clinical trial registration URL: https://www.clinicaltrials.gov. Unique identifier: NCT03057977.FK -3311 Icatibant related Iguratimod related KRP-203 related Leniolisib related Mycophenolate Mofetil related Mycophenolate Sodium Ozanimod Ridogrel Solupred Tofacitinib Metabolic Bone Disease Doxercalciferol related Etelcalcetide related Maxacalcitol related Risedronic Acid Ophthalmic Agents Alcaftadine related Bimatoprost related Brinzolamide related, 9/29/2020 · Suara.com - Obat antidiabetes golongan SGLT2 -- Empagliflozin, dipercaya memiliki manfaat bukan hanya untuk menurunkan kadar gula darah dalam tubuh tetapi juga juga memberikan efek perbaikan pada pasien gagal jantung. Dijelaskan oleh Prof. dr. Ketut Suastika dari FK Udayana Bali, awalnya SGLT2 adalah obat antidiabetes.canagliflozine vergelijken met een ander geneesmiddel.. Advies. Bij de behandeling van diabetes mellitus type 2 komen orale bloedglucoseverlagende middelen in aanmerking indien geen goede bloedglucoseregulatie wordt bereikt met voorlichting, aanpassing van de voeding, en stimulering van lichaamsbeweging. Metformine is eerste keus bij de medicamenteuze behandeling.12/4/2020 · Mod: dr. Zunilda Dj. Sadikin, MS, Sp. FK - New perspectives on recent cardiovascular outcome trial focus on Empagliflozin Prof. Dra. Arini Setiawati, Ph.D - Cost-effectiveness of Empagliflozin for the treatment of patients with type 2 diabetes mellitus at increased cardiovascular risk Prof. Dr. Dra. Erna Kristin, Apt, M.Si - Discussion: 11.40-13.00: Break
